Mm01250468_g1

• Gene Symbol: Arrb2
• Gene Name: arrestin, beta 2
• Gene Aliases: AI326910, AW122872
• Chromosome Location: Chr.11: 70432580 - 70440828 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Arrb2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001271358.1	NP_001258287.1	9 - 10	852		62
	NM_001271359.1	NP_001258288.1	9 - 10	852		62
	NM_001271360.1	NP_001258289.1	9 - 10	852		62
	NM_145429.5	NP_663404.1	9 - 10	852		62
GenBank mRNA	AK089542.1	-	9 - 10	788		62
	AK154874.1	-	9 - 10	772		62
	AK159317.1	-	9 - 10	780		62
	AK162889.1	-	9 - 10	789		62
	AK170647.1	-	9 - 10	799		62
	AK170889.1	-	9 - 10	762		62
	AK194092.1	-	1 - 2	45		62
	BC016642.1	-	9 - 10	734	2651372	62

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Arrb2

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

regulation of protein phosphorylation
positive regulation of protein phosphorylation
G-protein coupled receptor internalization
desensitization of G-protein coupled receptor protein signaling pathway by arrestin
positive regulation of receptor internalization
transcription from RNA polymerase II promoter
transport
endocytosis
signal transduction
transforming growth factor beta receptor signaling pathway
G-protein coupled receptor signaling pathway
adult walking behavior
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of signal transduction
protein transport
protein ubiquitination
negative regulation of protein ubiquitination
positive regulation of protein ubiquitination
receptor internalization
negative regulation of NF-kappaB transcription factor activity
positive regulation of synaptic transmission, dopaminergic
negative regulation of interleukin-1 beta production
negative regulation of interleukin-12 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of peptidyl-serine phosphorylation
negative regulation of toll-like receptor signaling pathway
negative regulation of GTPase activity
negative regulation of smooth muscle cell apoptotic process
follicle-stimulating hormone signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of peptidyl-tyrosine phosphorylation
detection of temperature stimulus involved in sensory perception of pain
positive regulation of protein kinase B signaling
positive regulation of calcium ion transport
cell chemotaxis
regulation of androgen receptor signaling pathway
positive regulation of ERK1 and ERK2 cascade
negative regulation of release of cytochrome c from mitochondria
positive regulation of DNA biosynthetic process

Function(s)

G-protein coupled receptor binding
receptor binding
protein binding
enzyme binding
protein domain specific binding
ubiquitin protein ligase binding
alpha-1A adrenergic receptor binding
alpha-1B adrenergic receptor binding
angiotensin receptor binding
type 1 angiotensin receptor binding
D1 dopamine receptor binding
follicle-stimulating hormone receptor binding
type 2A serotonin receptor binding
platelet activating factor receptor binding
protein complex binding
protein complex scaffold
protein kinase B binding
mitogen-activated protein kinase binding
14-3-3 protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100008337.mm.1	NM_001271358.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008337.mm.1	NM_001271359.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008337.mm.1	NM_001271360.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008337.mm.1	NM_145429.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008337.mm.1	TC1100000950.mm.1	MTA TC