Mm01250873_m1

• Gene Symbol: Dlg4
• Gene Name: discs, large homolog 4 (Drosophila)
• Gene Aliases: Dlgh4, PSD-95, PSD95, SAP90, SAP90A
• Chromosome Location: Chr.11: 70018455 - 70045532 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Dlg4
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001109752.1	NP_001103222.1	11 - 12	1610		75
	NM_007864.3	NP_031890.1	11 - 12	1619		75
GenBank mRNA	BC014807.1	-	11 - 12	1355	4501403	75
	D50621.1	-	11 - 12	1361		75

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100000937.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Dlg4

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

negative regulation of receptor internalization
protein complex assembly
signal transduction
positive regulation of cytosolic calcium ion concentration
chemical synaptic transmission
nervous system development
locomotory behavior
synaptic vesicle maturation
social behavior
protein localization to synapse
locomotory exploration behavior
response to cocaine
establishment of protein localization
nucleotide phosphorylation
regulation of neuronal synaptic plasticity
regulation of long-term neuronal synaptic plasticity
positive regulation of synaptic transmission
neuromuscular process controlling balance
dendritic spine morphogenesis
vocalization behavior
AMPA glutamate receptor clustering
receptor localization to synapse
regulation of N-methyl-D-aspartate selective glutamate receptor activity
positive regulation of excitatory postsynaptic potential
regulation of grooming behavior

Function(s)

guanylate kinase activity
receptor binding
structural molecule activity
protein binding
protein C-terminus binding
kinase binding
protein kinase binding
protein phosphatase binding
PDZ domain binding
beta-1 adrenergic receptor binding
D1 dopamine receptor binding
P2Y1 nucleotide receptor binding
protein complex binding
acetylcholine receptor binding
glutamate receptor binding
ionotropic glutamate receptor binding
neurexin family protein binding
neuroligin family protein binding
scaffold protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100008158.mm.1	NM_001109752.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008158.mm.1	NM_001109752.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008158.mm.1	NM_007864.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008158.mm.1	NM_007864.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008158.mm.1	TC1100000937.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100008159.mm.1	NM_001109752.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008159.mm.1	NM_001109752.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008159.mm.1	NM_007864.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008159.mm.1	NM_007864.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1100008159.mm.1	TC1100000937.mm.1	MTA TC