Mm01257351_g1 Best Coverage

• Gene Symbol: Mcl1
• Gene Name: myeloid cell leukemia sequence 1
• Gene Aliases: AW556805, Mcl-1
• Chromosome Location: Chr.3: 95658368 - 95663179 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Mcl1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008562.3	NP_032588.1	1 - 2	771		127
GenBank mRNA	AK159504.1	-	1 - 2	683		127
	BC003839.1	-	1 - 2	700	3491015	127
	BC005427.1	-	1 - 2	693	3493739	127
	BC021638.1	-	1 - 2	710	4190996	127
	GU182318.1	-	2 - 3	497		127
	U35623.1	-	1 - 2	683		127

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0300000910.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Mammalian Gene Collection, Detect Genomic DNA, Recommended Assay, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Mcl1

Gene Ontology Categories:

Process(es)

apoptotic process
multicellular organism development
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
cell differentiation
response to cytokine
regulation of apoptotic process
negative regulation of apoptotic process
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of anoikis
regulation of response to DNA damage stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
protein homodimerization activity
protein heterodimerization activity
protein dimerization activity
BH domain binding
BH3 domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0300007246.mm.1	NM_008562.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007246.mm.1	NM_008562.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007246.mm.1	TC0300000910.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300007248.mm.1	NM_008562.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007248.mm.1	NM_008562.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007248.mm.1	TC0300000910.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300007247.mm.1	NM_008562.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007247.mm.1	NM_008562.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007247.mm.1	TC0300000910.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300007242.mm.1	NM_008562.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007242.mm.1	NM_008562.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007242.mm.1	TC0300000910.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300007249.mm.1	NM_008562.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007249.mm.1	NM_008562.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007249.mm.1	TC0300000910.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300007245.mm.1	NM_008562.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007245.mm.1	NM_008562.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007245.mm.1	TC0300000910.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	665192	-	-