Mm01257352_g1

• Gene Symbol: Mcl1
• Gene Name: myeloid cell leukemia sequence 1
• Gene Aliases: AW556805, Mcl-1
• Chromosome Location: Chr.3: 95658368 - 95663179 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Mcl1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008562.3	NP_032588.1	2 - 3	1012		64
GenBank mRNA	AK010424.1	-	1 - 2	187		64
	AK159504.1	-	2 - 3	924		64
	AK160594.1	-	1 - 2	184		64
	BC003839.1	-	2 - 3	941	3491015	64
	BC005427.1	-	2 - 3	934	3493739	64
	BC021638.1	-	2 - 3	951	4190996	64
	GU182318.1	-	3 - 4	738		64
	U35623.1	-	2 - 3	924		64

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Apoptosis, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Mcl1

Gene Ontology Categories:

Process(es)

apoptotic process
multicellular organism development
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
cell differentiation
response to cytokine
regulation of apoptotic process
negative regulation of apoptotic process
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of anoikis
regulation of response to DNA damage stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
protein homodimerization activity
protein heterodimerization activity
protein dimerization activity
BH domain binding
BH3 domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0300007250.mm.1	NM_008562.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007250.mm.1	NM_008562.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007250.mm.1	TC0300000910.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300007252.mm.1	NM_008562.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007252.mm.1	NM_008562.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007252.mm.1	TC0300000910.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300007251.mm.1	NM_008562.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007251.mm.1	NM_008562.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300007251.mm.1	TC0300000910.mm.1	MTA TC