Mm01306292_m1 Best Coverage

• Gene Symbol: Srebf2
• Gene Name: sterol regulatory element binding factor 2
• Gene Aliases: AI608257, SREBP-2, SREBP2, SREBP2gc, bHLHd2, lop13, nuc
• Chromosome Location: Chr.15: 82147269 - 82205379 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Srebf2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_033218.1	NP_150087.1	1 - 2	223		64
GenBank mRNA	AF374267.1	-	1 - 2	76		64
	AK032847.1	-	1 - 2	247		64
	AK053802.1	-	1 - 2	242		64
	AK155857.1	-	1 - 2	291		64
	AK172219.1	-	1 - 2	228		64
	AK217643.1	-	1 - 2	140		64
	BC014730.1	-	1 - 2	213		64
	BC026556.1	-	1 - 2	215		64
	BC038284.1	-	1 - 2	214		64
	BC048071.1	-	1 - 2	228		64
	BC069989.1	-	1 - 2	232		64
	BQ965109.1	-	1 - 2	230		64

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1500000742.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Recommended Assay, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Srebf2

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
lipid metabolic process
steroid metabolic process
cholesterol metabolic process
cellular response to starvation
response to hormone
positive regulation of cholesterol storage
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
negative regulation of cholesterol efflux
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
regulation of cholesterol homeostasis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein C-terminus binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity
E-box binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1500005843.mm.1	NM_033218.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500005843.mm.1	NM_033218.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500005843.mm.1	TC1500000742.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1500005841.mm.1	NM_033218.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500005841.mm.1	NM_033218.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500005841.mm.1	TC1500000742.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1500005842.mm.1	NM_033218.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500005842.mm.1	NM_033218.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500005842.mm.1	TC1500000742.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1500005840.mm.1	NM_033218.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500005840.mm.1	NM_033218.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500005840.mm.1	TC1500000742.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1500005839.mm.1	NM_033218.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500005839.mm.1	NM_033218.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500005839.mm.1	TC1500000742.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	931530	-	-