Mm01325296_m1

• Gene Symbol: Alox12b
• Gene Name: arachidonate 12-lipoxygenase, 12R type
• Gene Aliases: Aloxe2, e-LOX2
• Chromosome Location: Chr.11: 69157072 - 69169791 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Alox12b
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_009659.2	NP_033789.1	12 - 13	1833		99
GenBank mRNA	AF059251.1	-	12 - 13	1711		99
	BC113149.1	-	12 - 13	1797	40054352	99
	Y14334.1	-	12 - 13	1833		99

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100000903.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Alox12b

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

protein lipidation
lipid metabolic process
fatty acid metabolic process
sphingolipid metabolic process
positive regulation of gene expression
arachidonic acid metabolic process
lipoxygenase pathway
positive regulation of MAPK cascade
linoleic acid metabolic process
ceramide biosynthetic process
hepoxilin biosynthetic process
oxidation-reduction process
establishment of skin barrier
positive regulation of mucus secretion
bicellular tight junction assembly

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
2,3-dihydroxy DDT 1,2-dioxygenase activity
phenanthrene dioxygenase activity
2,2',3-trihydroxybiphenyl dioxygenase activity
1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity
5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity
1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity
protocatechuate 3,4-dioxygenase type II activity
2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity
3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity
2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity
carbazole 1,9a-dioxygenase activity
dihydroxydibenzothiophene dioxygenase activity
1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity
styrene dioxygenase activity
3,4-dihydroxyphenanthrene dioxygenase activity
hydroquinone 1,2-dioxygenase activity
p-cumate 2,3-dioxygenase activity
2,3-dihydroxy-p-cumate dioxygenase activity
3,5-dichlorocatechol 1,2-dioxygenase activity
2-aminophenol 1,6-dioxygenase activity
2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity
chlorocatechol 1,2-dioxygenase activity
catechol dioxygenase activity
dihydroxyfluorene dioxygenase activity
5-aminosalicylate dioxygenase activity
3-hydroxy-2-naphthoate 2,3-dioxygenase activity
benzo(a)pyrene 11,12-dioxygenase activity
benzo(a)pyrene 4,5-dioxygenase activity
4,5-dihydroxybenzo(a)pyrene dioxygenase activity
benzo(a)pyrene 9,10-dioxygenase activity
9,10-dihydroxybenzo(a)pyrene dioxygenase activity
benzo(a)pyrene 7,8-dioxygenase activity
7,8-dihydroxy benzo(a)pyrene dioxygenase activity
1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity
2-mercaptobenzothiazole dioxygenase activity
pyridine-3,4-diol dioxygenase activity
pyrene dioxygenase activity
4,5-dihydroxypyrene dioxygenase activity
phenanthrene-4-carboxylate dioxygenase activity
tetrachlorobenzene dioxygenase activity
4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity
2,3-dihydroxydiphenyl ether dioxygenase activity
diphenyl ether 1,2-dioxygenase activity
arachidonate 8(S)-lipoxygenase activity
metal ion binding
4-hydroxycatechol 1,2-dioxygenase activity
dioxygenase activity
linoleate 9S-lipoxygenase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100007658.mm.1	NM_009659.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100007658.mm.1	NM_009659.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1100007658.mm.1	TC1100000903.mm.1	MTA TC