Mm01336544_m1

• Gene Symbol: Map2k4
• Gene Name: mitogen-activated protein kinase kinase 4
• Gene Aliases: JNKK1, MEK4, MKK4, PRKMK4, Sek1, Serk1
• Chromosome Location: Chr.11: 65688244 - 65788354 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Map2k4
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_009157.4	NP_033183.1	5 - 6	681		159
GenBank mRNA	AK036928.1	-	5 - 6	685		159
	AK044534.1	-	5 - 6	673		159
	AK044698.1	-	5 - 6	673		159
	AK139777.1	-	6 - 7	704		159
	BC029833.1	-	3 - 4	432	3962163	159
	U18310.1	-	5 - 6	656		159

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100002988.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Map2k4

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
positive regulation of protein phosphorylation
protein phosphorylation
apoptotic process
JNK cascade
activation of JUN kinase activity
phosphorylation
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of DNA replication
positive regulation of nitric-oxide synthase biosynthetic process
cell growth involved in cardiac muscle cell development

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
JUN kinase kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
mitogen-activated protein kinase kinase kinase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100027073.mm.1	NM_009157.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1100027073.mm.1	TC1100002988.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100027072.mm.1	NM_009157.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1100027072.mm.1	TC1100002988.mm.1	MTA TC