Rn00568900_m1 Best Coverage

• Gene Symbol: Gclm
• Gene Name: glutamate cysteine ligase, modifier subunit
• Gene Aliases: Glclr
• Chromosome Location: Chr.2: 225827504 - 225847876 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Gclm
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_017305.2	NP_059001.1	1 - 2	251		80
GenBank mRNA	BC078867.1	-	1 - 2	251	7110139	80
	L22191.1	-	1 - 2	189		80
	S65555.1	-	1 - 2	189		80

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0200002113.rn.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Gclm

Panther Classification:

Molecular Function -

ligase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

cysteine metabolic process
glutamate metabolic process
glutathione metabolic process
glutathione biosynthetic process
response to oxidative stress
apoptotic mitochondrial changes
positive regulation of glutamate-cysteine ligase activity
response to drug
negative regulation of neuron apoptotic process
regulation of blood vessel size
response to nitrosative stress
regulation of mitochondrial depolarization
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

glutamate-cysteine ligase activity
enzyme regulator activity
glutamate-cysteine ligase catalytic subunit binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21568443	-	-