Rn00575128_m1 Best Coverage

• Gene Symbol: Top1
• Gene Name: topoisomerase (DNA) I
• Gene Aliases: Ab2-086
• Chromosome Location: Chr.3: 156635688 - 156717686 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Top1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_022615.1	NP_072137.1	5 - 6	346		104
GenBank mRNA	AF140782.1	-	5 - 6	346		104

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect transcript(s) from off target gene(s). Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Detect Genomic DNA, Recommended Assay, Rattus norvegicus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Top1

Panther Classification:

Molecular Function -

DNA topoisomerase

Gene Ontology Categories:

Process(es)

DNA replication
DNA topological change
chromatin remodeling
chromosome segregation
circadian rhythm
response to temperature stimulus
rRNA transcription
response to gamma radiation
organ regeneration
circadian regulation of gene expression
embryonic cleavage
response to drug
response to cAMP
cellular response to luteinizing hormone stimulus

Function(s)

core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase type I activity
DNA topoisomerase type II (ATP-hydrolyzing) activity
chromatin DNA binding
protein complex binding
poly(A) RNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0300016453.rn.1	TC0300002215.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0300016452.rn.1	TC0300002215.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0300016455.rn.1	TC0300002215.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0300016454.rn.1	TC0300002215.rn.1	RTA TC