Rn00588658_g1 Best Coverage

• Gene Symbol: Mt3
• Gene Name: metallothionein 3
• Gene Aliases: GIF, Mt-3
• Chromosome Location: Chr.19: 11324708 - 11326112 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Mt3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_053968.3	NP_446420.1	2 - 3	158		58
GenBank mRNA	BC058453.1	-	2 - 3	161	6887014	58
	S65838.1	-	2 - 3	156		58
	X89603.1	-	2 - 3	95		58

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1900001018.rn.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, 3' Most, Mammalian Gene Collection, Detect Genomic DNA, Recommended Assay, Rattus norvegicus, Rat Hypoxia Panel, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Mt3

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
response to hypoxia
positive regulation of protein phosphorylation
energy reserve metabolic process
cholesterol catabolic process
zinc II ion transport
cellular metal ion homeostasis
cellular zinc ion homeostasis
response to oxidative stress
brain development
negative regulation of autophagy
positive regulation of gene expression
positive regulation of necrotic cell death
positive regulation of cell death
astrocyte development
histone modification
removal of superoxide radicals
negative regulation of cell growth
negative regulation of axon extension
positive regulation of vascular endothelial growth factor receptor signaling pathway
regulation of response to food
activation of protein kinase B activity
leptin-mediated signaling pathway
cellular response to oxidative stress
cellular response to drug
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
negative regulation of apoptotic process
positive regulation of catalytic activity
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
protein kinase B signaling
negative regulation of neuron apoptotic process
cellular lipid catabolic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of neurogenesis
negative regulation of dendrite morphogenesis
protein stabilization
negative regulation of oxidoreductase activity
zinc ion homeostasis
cadmium ion homeostasis
regulation of protein glycosylation
negative regulation of necrotic cell death
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
cellular response to cadmium ion
cellular response to hypoxia
cellular response to nitric oxide
positive regulation of lysosomal membrane permeability
negative regulation of neuron death
negative regulation of cysteine-type endopeptidase activity
negative regulation of hydrogen peroxide catabolic process
positive regulation of oxygen metabolic process
negative regulation of reactive oxygen species metabolic process

Function(s)

copper ion binding
drug binding
zinc ion binding
protein kinase activator activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
cadmium ion binding
metal ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_64_P134053	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	419732	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P134053	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P134053	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_64_P134053	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P1008888	-	-
Matsumoto (Agilent Rat cDNA Microarray G4105A)	700228221	-	-
Agilent Rat cDNA Microarray (G4105A)	700228221	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10809405	-	-
Affymetrix Rat Gene 1.0 ST Array	10809404	-	-
Affymetrix Rat Gene 1.0 ST Array	10809403	-	-
Affymetrix Rat Gene 1.1 ST Array	10809402	-	-
Rat Genome 230 2.0 Array	1370124_PM_at	-	-
Rat Genome 230 2.0 Array	1370124_at	-	-
Affymetrix HT Rat Focus Array	1370124_at	-	-
Affymetrix HT Rat Focus Array	1370124_PM_at	-	-
Affymetrix Rat Clariom S Assay	PSR1900008220.rn.1	TC1900001018.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1900008219.rn.1	TC1900001018.rn.1	RTA TC
Rat Expression Set 230	1370124_PM_at	-	-
Rat Expression Set 230	1370124_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10809402	-	-
Rat Genome U34 Set	rc_AA924772_at	-	-
Rat Genome U34 Set	rc_AA924772_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	22029340	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1374039	-	-
RatRef-12 Expression BeadChip	ILMN_51219	-	-