Rn00597992_m1 Best Coverage

• Gene Symbol: Bbc3
• Gene Name: Bcl-2 binding component 3
• Gene Aliases: Puma
• Chromosome Location: Chr.1: 78261491 - 78267802 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Bbc3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_173837.2	NP_776209.1		741		62
GenBank mRNA	AY157758.1	-		741		62

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0100000927.rn.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, 3' Most, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Bbc3

Gene Ontology Categories:

Process(es)

release of cytochrome c from mitochondria
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
brain development
determination of adult lifespan
glial cell differentiation
positive regulation of protein homooligomerization
negative regulation of endoplasmic reticulum calcium ion concentration
response to endoplasmic reticulum stress
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
negative regulation of growth
release of sequestered calcium ion into cytosol
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
positive regulation of thymocyte apoptotic process
cellular response to hypoxia
cellular response to ionizing radiation
positive regulation of release of cytochrome c from mitochondria
apoptotic signaling pathway
execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
toxin transport
positive regulation of cysteine-type endopeptidase activity
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_44_P437945	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P437945	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P437945	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_44_P437945	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P437945	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10940588	-	-
Affymetrix Rat Gene 1.1 ST Array	10940588	-	-
Rat Genome 230 2.0 Array	1382993_at	-	-
Rat Genome 230 2.0 Array	1382993_PM_at	-	-
Affymetrix HT Rat Focus Array	1382993_at	-	-
Affymetrix HT Rat Focus Array	1382993_PM_at	-	-
Affymetrix Rat Clariom S Assay	PSR0100006357.rn.1	TC0100000927.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0100006355.rn.1	TC0100000927.rn.1	RTA TC
Rat Expression Set 230	1382993_PM_at	-	-
Rat Expression Set 230	1382993_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10940588	-	-
Rat Genome U34 Set	rc_AI236152_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21722647	-	-