Rn00664883_m1

• Gene Symbol: Mgmt
• Gene Name: O-6-methylguanine-DNA methyltransferase
• Gene Aliases: -
• Chromosome Location: Chr.1: 209237255 - 209464189 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Mgmt
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_012861.1	NP_036993.1	2 - 3	191		148
GenBank mRNA	M76704.1	-	1 - 2	136		148
	S61804.1	-	2 - 3	191		148
	X54862.1	-	2 - 3	217		148

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0100002797.rn.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Mgmt

Gene Ontology Categories:

Process(es)

DNA repair
DNA dealkylation involved in DNA repair
cellular response to DNA damage stimulus
response to toxic substance
response to organic cyclic compound
methylation
cellular response to oxidative stress
response to drug
regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to ethanol
positive regulation of DNA repair
response to folic acid
negative regulation of cell death
mammary gland epithelial cell differentiation
cellular response to organic cyclic compound
cellular response to ionizing radiation

Function(s)

damaged DNA binding
methylated-DNA-[protein]-cysteine S-methyltransferase activity
calcium ion binding
methyltransferase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0100022028.rn.1	TC0100002797.rn.1	RTA TC