Rn01456874_g1 Best Coverage

• Gene Symbol: Arrb2
• Gene Name: arrestin, beta 2
• Gene Aliases: BARRES
• Chromosome Location: Chr.10: 57040252 - 57048045 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Arrb2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_012911.1	NP_037043.1	8 - 9	820		126
GenBank mRNA	BC087578.1	-	8 - 9	692	7311618	126
	M91590.1	-	8 - 9	820		126

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1000000962.rn.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Detect Genomic DNA, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Arrb2

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

regulation of protein phosphorylation
positive regulation of protein phosphorylation
G-protein coupled receptor internalization
desensitization of G-protein coupled receptor protein signaling pathway by arrestin
positive regulation of receptor internalization
transcription from RNA polymerase II promoter
endocytosis
transforming growth factor beta receptor signaling pathway
G-protein coupled receptor signaling pathway
brain development
adult walking behavior
regulation of G-protein coupled receptor protein signaling pathway
protein transport
protein ubiquitination
regulation of cAMP biosynthetic process
regulation of cAMP catabolic process
negative regulation of protein ubiquitination
positive regulation of protein ubiquitination
receptor internalization
negative regulation of NF-kappaB transcription factor activity
positive regulation of synaptic transmission, dopaminergic
negative regulation of interleukin-1 beta production
negative regulation of interleukin-12 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of peptidyl-serine phosphorylation
negative regulation of toll-like receptor signaling pathway
negative regulation of GTPase activity
negative regulation of smooth muscle cell apoptotic process
follicle-stimulating hormone signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of peptidyl-tyrosine phosphorylation
detection of temperature stimulus involved in sensory perception of pain
positive regulation of protein kinase B signaling
positive regulation of calcium ion transport
cell chemotaxis
regulation of androgen receptor signaling pathway
positive regulation of ERK1 and ERK2 cascade
negative regulation of release of cytochrome c from mitochondria
positive regulation of DNA biosynthetic process

Function(s)

G-protein coupled receptor binding
receptor binding
protein binding
enzyme binding
protein domain specific binding
clathrin binding
ubiquitin protein ligase binding
alpha-1A adrenergic receptor binding
alpha-1B adrenergic receptor binding
angiotensin receptor binding
type 1 angiotensin receptor binding
D1 dopamine receptor binding
follicle-stimulating hormone receptor binding
type 2A serotonin receptor binding
protein complex binding
protein complex scaffold
protein kinase B binding
mitogen-activated protein kinase binding
14-3-3 protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_42_P792129	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	280947	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	37190	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	874667	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	367474	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	72948	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_42_P792129	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_42_P792129	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_42_P792129	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P379214	-	-
Matsumoto (Agilent Rat cDNA Microarray G4105A)	700478778	-	-
Matsumoto (Agilent Rat cDNA Microarray G4105A)	702240651	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	42045	-	-
Agilent Rat cDNA Microarray (G4105A)	700478778	-	-
Agilent Rat cDNA Microarray (G4105A)	702240651	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10735210	-	-
Affymetrix Rat Gene 1.0 ST Array	10735213	-	-
Affymetrix Rat Gene 1.0 ST Array	10735207	-	-
Affymetrix Rat Gene 1.0 ST Array	10735206	-	-
Affymetrix Rat Gene 1.0 ST Array	10735208	-	-
Affymetrix Rat Gene 1.0 ST Array	10735212	-	-
Affymetrix Rat Gene 1.0 ST Array	10735209	-	-
Affymetrix Rat Gene 1.0 ST Array	10735215	-	-
Affymetrix Rat Gene 1.0 ST Array	10735211	-	-
Affymetrix Rat Gene 1.0 ST Array	10735216	-	-
Affymetrix Rat Gene 1.1 ST Array	10735205	-	-
Rat Genome 230 2.0 Array	1370265_at	-	-
Rat Genome 230 2.0 Array	1370265_PM_at	-	-
Affymetrix HT Rat Focus Array	1370265_PM_at	-	-
Affymetrix HT Rat Focus Array	1370265_at	-	-
Affymetrix Rat Clariom S Assay	PSR1000008495.rn.1	TC1000000962.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1000008494.rn.1	TC1000000962.rn.1	RTA TC
Rat Expression Set 230	1370265_at	-	-
Rat Expression Set 230	1370265_PM_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10735205	-	-
Rat Genome U34 Set	M91590_at	-	-
Rat Genome U34 Set	M91590_g_at	-	-
Rat Genome U34 Set	rc_AI013765_s_at	-	-
Rat Genome U34 Set	rc_AA964003_s_at	-	-
Rat Genome U34 Set	rc_AI136065_i_at	-	-
Rat Genome U34 Set	rc_AI136065_s_at	-	-
Rat Genome U34 Set	rc_AI178546_at	-	-
Rat Genome U34 Set	M91590_g_at	-	-
Rat Genome U34 Set	rc_AI136065_s_at	-	-
Rat Genome U34 Set	M91590_at	-	-
Rat Genome U34 Set	rc_AA964003_s_at	-	-
Rat Genome U34 Set	rc_AI013765_s_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21321099	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1370634	-	-
RatRef-12 Expression BeadChip	ILMN_56088	-	-