Rn01461081_m1 Best Coverage

• Gene Symbol: Alox12
• Gene Name: arachidonate 12-lipoxygenase
• Gene Aliases: 12-LO, 12S-LOX
• Chromosome Location: Chr.10: 56851734 - 56864047 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Alox12
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001105798.1	NP_001099268.1	6 - 7	847		79
	XM_006246659.2	XP_006246721.1	6 - 7	889		79
GenBank mRNA	BC168184.1	-	6 - 7	847	7098799	79

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1000003123.rn.1

• Set Membership: Amplicon length between 71 and 85, Mammalian Gene Collection, Recommended Assay, Rattus norvegicus, Probe spans exons

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

aging
positive regulation of cell proliferation
positive regulation of endothelial cell migration
positive regulation of gene expression
negative regulation of muscle cell apoptotic process
positive regulation of cell death
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
positive regulation of cell growth
positive regulation of cell migration
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
linoleic acid metabolic process
positive regulation of endothelial cell differentiation
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of vasodilation
positive regulation of smooth muscle cell proliferation
hepoxilin biosynthetic process
positive regulation of mitochondrial depolarization
oxidation-reduction process
establishment of skin barrier
cellular response to lipid
negative regulation of platelet aggregation
leukotriene A4 metabolic process
lipoxin A4 biosynthetic process
lipoxin B4 biosynthetic process

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
linoleate 13S-lipoxygenase activity
hydrolase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR1000028033.rn.1	TC1000003123.rn.1	RTA TC