Rn01473654_g1

• Gene Symbol: Nfkbia
• Gene Name: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
• Gene Aliases: RL/IF-1
• Chromosome Location: Chr.6: 76267227 - 76270457 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Nfkbia
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001105720.2	NP_001099190.2	3 - 4	667		108
GenBank mRNA	BC166886.1	-	3 - 4	619	6890357	108
	CB316505.1	-	3 - 4	621		108
	FQ214065.1	-	1 - 2	115		108
	FQ215246.1	-	3 - 4	619		108
	FQ225350.1	-	3 - 4	614		108
	FQ225877.1	-	3 - 4	617		108
	FQ227283.1	-	3 - 4	617		108
	FQ233200.1	-	3 - 4	617		108
	FQ233557.1	-	3 - 4	619		108
	FQ233627.1	-	3 - 4	605		108
	FQ234262.1	-	3 - 4	619		108
	X63594.1	-	3 - 4	597		108

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0600002478.rn.1

• Set Membership: Amplicon length greater than or equal to 101, Apoptosis, Mammalian Gene Collection, Detect Genomic DNA, Rattus norvegicus, Probe spans exons

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
cytoplasmic sequestering of NF-kappaB
regulation of gene expression
negative regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol efflux
negative regulation of lipid storage
lipopolysaccharide-mediated signaling pathway
negative regulation of NF-kappaB transcription factor activity
positive regulation of cellular protein metabolic process
response to muramyl dipeptide
response to lipopolysaccharide
toll-like receptor 4 signaling pathway
response to muscle stretch
regulation of cell proliferation
cytoplasmic sequestering of transcription factor
response to exogenous dsRNA
negative regulation of myeloid cell differentiation
negative regulation of Notch signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
nucleotide-binding oligomerization domain containing 1 signaling pathway
nucleotide-binding oligomerization domain containing 2 signaling pathway

Function(s)

nuclear localization sequence binding
enzyme binding
heat shock protein binding
ubiquitin protein ligase binding
protein complex binding
identical protein binding
NF-kappaB binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0600017682.rn.1	TC0600002478.rn.1	RTA TC