Rn01495769_m1 Best Coverage

• Gene Symbol: Srebf1
• Gene Name: sterol regulatory element binding transcription factor 1
• Gene Aliases: ADD-1, ADD1, SREBP-1, SREBP-1c, Srebp1
• Chromosome Location: Chr.10: 46570996 - 46593009 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Srebf1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001276707.1	NP_001263636.1	5 - 6	1126		79
	NM_001276708.1	NP_001263637.1	5 - 6	1013		79
	XM_008767879.1	XP_008766101.1	5 - 6	1266		79
GenBank mRNA	AF286469.2	-	5 - 6	980		79
	AF286470.2	-	5 - 6	980		79

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1000002930.rn.1

• Set Membership: Amplicon length between 71 and 85, Recommended Assay, Rattus norvegicus, Inventoried, Probe spans exons

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of heart rate by chemical signal
transcription, DNA-templated
regulation of transcription, DNA-templated
aging
circadian rhythm
cholesterol metabolic process
insulin receptor signaling pathway
lipid biosynthetic process
cellular response to starvation
response to glucose
positive regulation of triglyceride biosynthetic process
response to organic cyclic compound
regulation of fatty acid metabolic process
lung development
positive regulation of histone deacetylation
response to food
response to retinoic acid
response to progesterone
response to insulin
cellular response to insulin stimulus
response to glucagon
response to lipid
response to drug
response to peptide hormone
positive regulation of cholesterol biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of insulin secretion
regulation of insulin secretion
response to cAMP
response to fatty acid
cellular response to fatty acid

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein kinase binding
protein complex binding
sterol response element binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR1000025729.rn.1	TC1000002930.rn.1	RTA TC