Rn01525753_g1 Best Coverage

• Gene Symbol: Ager
• Gene Name: advanced glycosylation end product-specific receptor
• Gene Aliases: RAGE
• Chromosome Location: Chr.20: 4363152 - 4366079 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ager
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_053336.2	NP_445788.2	4 - 5	470		63
	XM_006256025.1	XP_006256087.1	4 - 5	453		63
GenBank mRNA	BC084697.1	-	4 - 5	452	7121345	63
	GU164715.1	-	2 - 3	810		63
	GU164716.1	-	3 - 4	637		63
	GU164717.1	-	4 - 5	436		63
	L33413.1	-	4 - 5	470		63

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC2000000148.rn.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Detect Genomic DNA, Recommended Assay, Rattus norvegicus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ager

Panther Classification:

Molecular Function -

cell adhesion molecule, immunoglobulin superfamily cell adhesion molecule

Gene Ontology Categories:

Process(es)

response to hypoxia
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
negative regulation of endothelial cell proliferation
inflammatory response
negative regulation of cell adhesion
JAK-STAT cascade
brain development
glycoprotein metabolic process
response to fructose
positive regulation of autophagy
negative regulation of endothelial cell migration
positive regulation of gene expression
positive regulation of epithelial to mesenchymal transition
positive regulation of fibroblast migration
response to activity
positive regulation of smooth muscle cell migration
lung development
positive regulation of cell migration
neuron projection development
negative regulation of collagen biosynthetic process
response to vitamin A
response to genistein
negative regulation of osteoblast proliferation
cellular response to drug
positive regulation of apoptotic process
positive regulation of JUN kinase activity
positive regulation of neuron apoptotic process
positive regulation of fibroblast proliferation
positive regulation of smooth muscle cell proliferation
regulation of inflammatory response
positive regulation of inflammatory response
induction of positive chemotaxis
positive regulation of NF-kappaB transcription factor activity
regulation of DNA binding
response to methylglyoxal
calcium ion homeostasis
response to hyperoxia
positive regulation of phagocytosis, engulfment
transdifferentiation
cellular response to hydrogen peroxide
cellular response to glucose stimulus
cellular response to fatty acid
cellular response to organic cyclic compound
protein localization to membrane
response to selenite ion
positive regulation of potassium ion transmembrane transporter activity
positive regulation of neuron death
positive regulation of endothelial cell apoptotic process
positive regulation of reactive oxygen species metabolic process
positive regulation of type B pancreatic cell apoptotic process

Function(s)

protein binding
identical protein binding
S100 protein binding
advanced glycation end-product receptor activity
high mobility group box 1 binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR2000001351.rn.1	TC2000000148.rn.1	RTA TC