Ss03391838_g1 Best Coverage

• Gene Symbol: PRNP
• Gene Name: prion protein
• Gene Aliases: PRP
• Chromosome Location: Chr.17: 13694195 - 13705126 on Build Sscrofa11.1
• Species: Pig
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PRNP
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001008687.1	NP_001008687.1	1	652		81
	XM_005672669.2	XP_005672726.1		941		81
	XM_013985024.2	XP_013840478.1		889		81
	XM_013985025.2	XP_013840479.1		776		81
GenBank mRNA	AK235358.1	-	2	712		81

More Information

• Set Membership: Amplicon length between 71 and 85, 3' Most, Detect Genomic DNA, Recommended Assay, Sus scrofa, Inventoried, Both primers and probe map within a single exon

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
response to oxidative stress
learning or memory
negative regulation of endopeptidase activity
protein destabilization
activation of protein kinase activity
negative regulation of interferon-gamma production
negative regulation of interleukin-17 production
negative regulation of interleukin-2 production
calcium-mediated signaling using intracellular calcium source
cellular response to drug
negative regulation of apoptotic process
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neuron apoptotic process
negative regulation of activated T cell proliferation
negative regulation of T cell receptor signaling pathway
protein homooligomerization
positive regulation of protein tyrosine kinase activity
negative regulation of calcineurin-NFAT signaling cascade
cellular response to copper ion
positive regulation of protein targeting to membrane
modulation of age-related behavioral decline
regulation of glutamate receptor signaling pathway
regulation of potassium ion transmembrane transport
negative regulation of beta-amyloid formation
regulation of intracellular calcium activated chloride channel activity
negative regulation of dendritic spine maintenance
positive regulation of protein localization to plasma membrane
cellular response to beta-amyloid
regulation of calcium ion import across plasma membrane
neuron projection maintenance

Function(s)

beta-amyloid binding
protease binding
copper ion binding
glycosaminoglycan binding
microtubule binding
tubulin binding
aspartic-type endopeptidase inhibitor activity
type 5 metabotropic glutamate receptor binding
signaling receptor activity
identical protein binding
macromolecular complex binding
cupric ion binding
cuprous ion binding