C_321527242_10

• SNP ID: rs775867068
• Gene: ALKBH3
• Gene Name: alkB homolog 3, alpha-ketoglutaratedependent dioxygenase
• Set Membership: -
• Chromosome Location: Chr.11: 43881136 - 43881136 on Build GRCh38
• Polymorphism: A/G, Transition substitution
• Context Sequence [VIC/FAM]:

  TTAGTCTGCACCTCAACCGTGCGGA[A/G]AGTGACTGCCCTGTTTACTGAGGAA

Assay Details

Species:	Human
dbSNP Submissions:	NA
Phenotype:	MIM: 610603
Literature Links:	ALKBH3 PubMed Links
Allele Nomenclature:
Minor Allele Frequency:

1000Genome	Applied Biosystems^®	HapMap
Global - Not Available	Caucasian - Not Available	CEPH (CEU) - Not Available
EAS - Not Available	African American - Not Available	YRI (Yoruba) - Not Available
SAS - Not Available	Chinese - Not Available	CHB (Han Chinese) - Not Available
AFR - Not Available	Japanese - Not Available	JPT (Japanese) - Not Available
EUR - Not Available
AMR - Not Available

ALKBH3 - alkB homolog 3, alpha-ketoglutaratedependent dioxygenase
Transcript Accession	SNP Location	SNP Type	Observed Codons	Observed Amino Acid	Protein ID
NM_139178.3	330	UTR 5			NP_631917.1

More Information

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

DNA repair
DNA dealkylation involved in DNA repair
cell proliferation
oxidative single-stranded DNA demethylation
oxidative single-stranded RNA demethylation

Function(s)

protein binding
ferrous iron binding
L-ascorbic acid binding
DNA-N1-methyladenine dioxygenase activity
cytosine C-5 DNA demethylase activity
RNA N1-methyladenosine dioxygenase activity