C__29080920_10

SNP ID:

rs8062460

Gene

BFAR PLA2G10

Gene Name

bifunctional apoptosis regulator

phospholipase A2 group X

Set Membership:

> HapMap

Chromosome Location:

Chr.16: 14665911 - 14665911 on Build GRCh38

Polymorphism:

A/G, Transition substitution

Context Sequence [VIC/FAM]:

GCATGAGTTCTAATCCTGATCTGTA[A/G]CCAACTAGGATAATAATAACTTAGG

Assay Details

Species:	Human
dbSNP Submissions:	NA
Phenotype:	MIM: 603603
Literature Links:	BFAR PubMed Links
Allele Nomenclature:
Minor Allele Frequency:

1000Genome	Applied Biosystems^®	HapMap
Global G (0.14) (0.86)	Caucasian - Not Available	CEPH (CEU) G (0.09) (0.91)
EAS G (0.21) (0.79)	African American - Not Available	YRI (Yoruba) G (0.14) (0.86)
SAS G (0.16) (0.84)	Chinese - Not Available	JPT (Japanese) G (0.13) (0.87)
AFR G (0.12) (0.88)	Japanese - Not Available	CHB (Han Chinese) G (0.14) (0.86)
EUR G (0.10) (0.90)
AMR G (0.08) (0.92)

BFAR - bifunctional apoptosis regulator
Transcript Accession	SNP Location	SNP Type	Observed Codons	Observed Amino Acid	Protein ID
NM_016561.2		Intron			NP_057645.1
XM_005255350.2		Intron			XP_005255407.1
XM_011522520.1		Intron			XP_011520822.1

PLA2G10 - phospholipase A2 group X
There are no transcripts associated with this gene.

More Information

• Set Membership: HapMap

Gene Ontology Categories:

Process(es)

protein polyubiquitination
apoptotic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein autoubiquitination
protein K63-linked ubiquitination
protein K48-linked ubiquitination
negative regulation of IRE1-mediated unfolded protein response

Function(s)

protein binding
zinc ion binding
protein binding, bridging
ubiquitin protein ligase activity
caspase binding