100458

• Gene Symbol: Bax
• Gene Name: BCL2-associated X protein
• Gene Aliases: -
• Chromosome Location: Chr.7: 45461695 - 45466903 on Build GRCm38
• UniGene ID: Mm.19904
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Bax
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007527.3	NP_031553.1	4, 5	500
GenBank mRNA	AK013298.1	-	4, 5	410
	AK149994.1	-	4, 5	393
	AK159233.1	-	4, 5	465
	AY095934.1	-	3, 4	847
	BC018228.1	-	4, 5	445	3968903
	BC053380.1	-	4, 5	417	6489475
	L22472.1	-	4, 5	377

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017059, AF235993, CB586216, U32098, S76511, and others.

Gene Ontology Categories:

Process(es)

ovarian follicle development
neuron migration
leukocyte homeostasis
T cell homeostatic proliferation
B cell homeostasis
B cell apoptotic process
kidney development
release of cytochrome c from mitochondria
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
blood vessel remodeling
myeloid cell homeostasis
B cell negative selection
B cell homeostatic proliferation
positive regulation of B cell apoptotic process
glycosphingolipid metabolic process
regulation of nitrogen utilization
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
obsolete transformed cell apoptotic process
cellular response to DNA damage stimulus
inner mitochondrial membrane organization
outer mitochondrial membrane organization
germ cell development
spermatogenesis
nervous system development
sex differentiation
mitochondrial fusion
cell proliferation
negative regulation of cell proliferation
male gonad development
extrinsic apoptotic signaling pathway via death domain receptors
intrinsic apoptotic signaling pathway in response to DNA damage
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
apoptotic mitochondrial changes
fertilization
response to wounding
response to toxic substance
response to salt stress
post-embryonic development
response to ionizing radiation
establishment or maintenance of transmembrane electrochemical gradient
response to gamma radiation
positive regulation of calcium ion transport into cytosol
hypothalamus development
cerebral cortex development
negative regulation of protein binding
positive regulation of protein oligomerization
negative regulation of endoplasmic reticulum calcium ion concentration
release of matrix enzymes from mitochondria
negative regulation of peptidyl-serine phosphorylation
regulation of mammary gland epithelial cell proliferation
cellular response to UV
limb morphogenesis
ectopic germ cell programmed cell death
odontogenesis of dentin-containing tooth
regulation of apoptotic process
positive regulation of apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of protein homodimerization activity
regulation of protein heterodimerization activity
regulation of neuron apoptotic process
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
mitochondrial fragmentation involved in apoptotic process
development of secondary sexual characteristics
cellular respiration
retinal cell programmed cell death
positive regulation of developmental pigmentation
negative regulation of fibroblast proliferation
spermatid differentiation
post-embryonic camera-type eye morphogenesis
response to axon injury
homeostasis of number of cells
homeostasis of number of cells within a tissue
protein oligomerization
protein homooligomerization
positive regulation of release of sequestered calcium ion into cytosol
neuron apoptotic process
regulation of cell cycle
regulation of mitochondrial membrane potential
transmembrane transport
Sertoli cell proliferation
retina development in camera-type eye
positive regulation of apoptotic process involved in mammary gland involution
vagina development
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
thymocyte apoptotic process
mitochondrion morphogenesis
cellular response to organic substance
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
intrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
positive regulation of endoplasmic reticulum unfolded protein response
regulation of mitochondrial membrane permeability involved in apoptotic process
positive regulation of mitochondrial membrane permeability involved in apoptotic process
apoptotic process involved in patterning of blood vessels
apoptotic process involved in embryonic digit morphogenesis
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
positive regulation of apoptotic DNA fragmentation
retinal cell apoptotic process
B cell receptor apoptotic signaling pathway
negative regulation of apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
lipid binding
channel activity
heat shock protein binding
protein complex binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity
chaperone binding
BH domain binding
BH3 domain binding