101539

• Gene Symbol: Hes5
• Gene Name: hairy and enhancer of split 5 (Drosophila)
• Gene Aliases: bHLHb38
• Chromosome Location: Chr.4: 154958680 - 154962372 on Build GRCm38
• UniGene ID: Mm.137268
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hes5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010419.4	NP_034549.1	2	281
GenBank mRNA	AK078170.1	-	2	284
	AK087508.1	-	2	282
	AK139390.1	-	2	283
	AK156545.1	-	2	283
	BC099863.1	-	2	233	40039952
	BC099864.1	-	2	233	40039951
	BC099865.1	-	2	233	40039949
	BC103539.1	-	2	231	40039948

More Information

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
chondrocyte differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
cell adhesion
Notch signaling pathway
smoothened signaling pathway
multicellular organism development
nervous system development
brain development
positive regulation of cell proliferation
oligodendrocyte development
telencephalon development
glial cell fate commitment
forebrain radial glial cell differentiation
neural tube development
central nervous system myelination
cell differentiation
positive regulation of BMP signaling pathway
regulation of myelination
auditory receptor cell differentiation
positive regulation of tyrosine phosphorylation of Stat3 protein
auditory receptor cell fate determination
camera-type eye development
regulation of cell differentiation
negative regulation of neuron differentiation
positive regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JAK-STAT cascade
cell maturation
positive regulation of smooth muscle cell proliferation
astrocyte differentiation
negative regulation of astrocyte differentiation
negative regulation of oligodendrocyte differentiation
regulation of neurogenesis
cartilage development
neuronal stem cell population maintenance
negative regulation of stem cell differentiation
negative regulation of pro-B cell differentiation
negative regulation of forebrain neuron differentiation
negative regulation of inner ear receptor cell differentiation

Function(s)

transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
double-stranded DNA binding
protein binding
transcription factor binding
protein dimerization activity