103507 Validated

• Gene Symbol: TLK2
• Gene Name: tousled like kinase 2
• Gene Aliases: HsHPK, PKU-ALPHA
• Chromosome Location: Chr.17: 62477481 - 62615481 on Build GRCh38
• UniGene ID: Hs.445078
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TLK2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001284333.1	NP_001271262.1	12	1251
	NM_001284363.1	NP_001271292.1	10	912
	NM_006852.3	NP_006843.2	12	1254
	XM_011524215.2	XP_011522517.1	10	895
	XM_011524216.2	XP_011522518.1	12	1015
	XM_011524217.2	XP_011522519.1	12	1202
	XM_011524218.2	XP_011522520.1	10	895
	XM_011524220.2	XP_011522522.1	9	799
	XM_011524221.2	XP_011522523.1	11	913
	XM_011524222.2	XP_011522524.1	12	1394
	XM_011524223.2	XP_011522525.1	10	1056
	XM_011524224.2	XP_011522526.1	10	1114
	XM_011524225.2	XP_011522527.1	10	1062
	XM_011524226.2	XP_011522528.1	12	1108
	XM_011524227.2	XP_011522529.1	11	1162
	XM_011524228.2	XP_011522530.1	12	1262
	XM_011524229.2	XP_011522531.1	13	1189
	XM_011524231.1	XP_011522533.1	11	988
	XM_017024044.1	XP_016879533.1	12	1088
	XM_017024045.1	XP_016879534.1	11	1196
	XM_017024046.1	XP_016879535.1	12	1018
	XM_017024047.1	XP_016879536.1	12	1015
	XM_017024048.1	XP_016879537.1	11	1410
	XM_017024049.1	XP_016879538.1	11	1363
	XM_017024050.1	XP_016879539.1	10	961
	XM_017024051.1	XP_016879540.1	11	1410
	XM_017024052.1	XP_016879541.1	11	1361
	XM_017024053.1	XP_016879542.1	11	1033
	XM_017024054.1	XP_016879543.1	10	1059
	XM_017024055.1	XP_016879544.1	9	963
	XM_017024056.1	XP_016879545.1	10	1114
	XM_017024057.1	XP_016879546.1	10	928
	XM_017024058.1	XP_016879547.1	12	1206
	XM_017024059.1	XP_016879548.1	12	1196
	XM_017024060.1	XP_016879549.1	11	1113
GenBank mRNA	AB004884.1	-	10	890
	AF162667.1	-	12	1126
	AK300586.1	-	10	912
	AX775745.1	-	12	1126
	BC044925.1	-	12	1158

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191652, XM_006247576, XM_008768350, XM_006247574, XM_008768348, and others.
This siRNA also targets the following transcripts in Mouse: NM_001294334, NM_001112705, NM_001294330, NM_001294331, NM_001294329, and others.

Matching Taqman Gene Expression Assay:

Hs00851784_g1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

regulation of chromatin assembly or disassembly
protein phosphorylation
cellular response to DNA damage stimulus
cell cycle
chromosome segregation
negative regulation of autophagy
covalent chromatin modification
peptidyl-serine phosphorylation
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
intracellular signal transduction
cellular response to gamma radiation

Function(s)

protein serine/threonine kinase activity
protein binding
ATP binding