103580

• Gene Symbol: MAP2K4
• Gene Name: mitogen-activated protein kinase kinase 4
• Gene Aliases: JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1
• Chromosome Location: Chr.17: 12020818 - 12143831 on Build GRCh38
• UniGene ID: Hs.514681
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MAP2K4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001281435.1	NP_001268364.1	4	441
	NM_003010.3	NP_003001.1	3	408
	XM_005256753.2	XP_005256810.1	2	247
	XM_011523976.2	XP_011522278.1	4	425
GenBank mRNA	AK131544.1	-	4	426
	AK294923.1	-	4	284
	AK313053.1	-	3	361
	AK316100.1	-	2	175
	BC036032.1	-	3	408	5272439
	BC060764.1	-	3	402	5294838
	BT019676.1	-	3	339
	CR536564.1	-	3	339
	L36870.1	-	3	348
	U17743.1	-	3	359

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001030023, AY880882, KC795688.
This siRNA also targets the following transcripts in Mouse: NM_009157, AK044534, AK139777, BC029833, AK044698, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

apoptotic process
signal transduction
JNK cascade
response to wounding
peptidyl-tyrosine phosphorylation
proteolysis in other organism
Fc-epsilon receptor signaling pathway
cellular response to mechanical stimulus
negative regulation of motor neuron apoptotic process

Function(s)

protein kinase activity
receptor signaling protein serine/threonine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding