105220

• Gene Symbol: NLRC4
• Gene Name: NLR family CARD domain containing 4
• Gene Aliases: AIFEC, CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, FCAS4, IPAF
• Chromosome Location: Chr.2: 32224449 - 32265743 on Build GRCh38
• UniGene ID: Hs.574741
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NLRC4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001199138.1	NP_001186067.1	3, 4	515
	NM_001199139.1	NP_001186068.1	3, 4	398
	NM_001302504.1	NP_001289433.1	3, 4	529
	NM_021209.4	NP_067032.3	3, 4	529
	XM_017004619.1	XP_016860108.1	3, 4	515
GenBank mRNA	AF376061.1	-	4, 5	743
	AK095467.1	-	3, 4	515
	AK292673.1	-	3, 4	500
	AK314762.1	-	3, 4	500
	AY027787.1	-	3, 4	530
	AY027788.1	-	3, 4	530
	AY027789.1	-	3, 4	530
	AY027790.1	-	3	530
	AY032589.1	-	2, 3	289
	AY035391.1	-	3, 4	398
	AY358152.1	-	3, 4	477
	BC031555.1	-	3, 4	485	5179909
	DN998613.1	-	3, 4	535

More Information

Gene Ontology Categories:

Process(es)

activation of innate immune response
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
regulation of signal transduction
detection of bacterium
protein ubiquitination
defense response to bacterium
regulation of apoptotic process
positive regulation of apoptotic process
innate immune response
interleukin-1 beta secretion
positive regulation of NF-kappaB transcription factor activity
protein homooligomerization
pyroptosis
mitotic spindle assembly
inhibition of cysteine-type endopeptidase activity involved in apoptotic process

Function(s)

magnesium ion binding
ubiquitin-protein transferase activity
cysteine-type endopeptidase inhibitor activity
protein binding
ATP binding
identical protein binding
protein homodimerization activity