105221

• Gene Symbol: NLRC4
• Gene Name: NLR family CARD domain containing 4
• Gene Aliases: AIFEC, CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, FCAS4, IPAF
• Chromosome Location: Chr.2: 32224449 - 32265743 on Build GRCh38
• UniGene ID: Hs.574741
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NLRC4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001199138.1	NP_001186067.1	6	2687
	NM_001199139.1	NP_001186068.1	6	2570
	NM_001302504.1	NP_001289433.1	5	706
	NM_021209.4	NP_067032.3	6	2701
GenBank mRNA	AF376061.1	-	7	2915
	AK095467.1	-	6	2687
	AK292673.1	-	6	2672
	AK314762.1	-	6	2672
	AL389934.1	-	3	672
	AY027787.1	-	6	2702
	AY027788.1	-	5	707
	AY032589.1	-	5	2461
	AY035391.1	-	6	2570
	AY358152.1	-	6	2649
	BC031555.1	-	6	2657	5179909

More Information

Gene Ontology Categories:

Process(es)

activation of innate immune response
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
regulation of signal transduction
detection of bacterium
protein ubiquitination
defense response to bacterium
regulation of apoptotic process
positive regulation of apoptotic process
innate immune response
interleukin-1 beta secretion
positive regulation of NF-kappaB transcription factor activity
protein homooligomerization
pyroptosis
mitotic spindle assembly
inhibition of cysteine-type endopeptidase activity involved in apoptotic process

Function(s)

magnesium ion binding
ubiquitin-protein transferase activity
cysteine-type endopeptidase inhibitor activity
protein binding
ATP binding
identical protein binding
protein homodimerization activity