10581

• Gene Symbol: CTH
• Gene Name: cystathionine gamma-lyase
• Gene Aliases: -
• Chromosome Location: Chr.1: 70411218 - 70441949 on Build GRCh38
• UniGene ID: Hs.19904
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CTH
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001902.5	NP_001893.2	3	474
	NM_153742.4	NP_714964.2	3	474
	XM_005270509.3	XP_005270566.1	3	494
GenBank mRNA	AK223376.1	-	3	447
	AK310269.1	-	3	462
	BC015807.2	-	3	420	3915913
	BT006882.1	-	3	276
	S52028.1	-	3	309
	S52784.1	-	3	309

More Information

Panther Classification:

Molecular Function -

lyase

Gene Ontology Categories:

Process(es)

sulfur amino acid catabolic process
cysteine metabolic process
protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine
cysteine biosynthetic process via cystathionine
cysteine biosynthetic process
transsulfuration
endoplasmic reticulum unfolded protein response
positive regulation of I-kappaB kinase/NF-kappaB signaling
protein sulfhydration
positive regulation of NF-kappaB transcription factor activity
protein homotetramerization
hydrogen sulfide biosynthetic process
'de novo' L-methionine biosynthetic process
positive regulation of aortic smooth muscle cell differentiation
negative regulation of apoptotic signaling pathway

Function(s)

cystathionine gamma-synthase activity
cystathionine gamma-lyase activity
protein binding
calmodulin binding
carbon-sulfur lyase activity
pyridoxal phosphate binding
L-cystine L-cysteine-lyase (deaminating)
homocysteine desulfhydrase activity
L-cysteine desulfhydrase activity