105953

Gene Symbol:

CYP2D6 CYP2D7 LOC101929829

Gene Name:

cytochrome P450 family 2 subfamily D member 6

cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)

cytochrome P450 family 2 subfamily D member 6 pseudogene

Gene Aliases:

CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1

CYP2D, CYP2D7AP, CYP2D7P, CYP2D7P1, CYP2D@, P450C2D, P450DB1, RNA40057

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Chromosome Location:

Chr.22: 42125531 - 42130881 on Build GRCh38

Chromosome Location:

Chr.22: 42140203 - 42144575 on Build GRCh38

Chromosome Location:

-

UniGene ID:

Hs.648256

Hs.333497

Hs.648256

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: CYP2D6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000106.5	NP_000097.3	7, 8	1271
	NM_001025161.2	NP_001020332.2	6, 7	1118
	XM_011529966.2	XP_011528268.1	7, 8	1265
	XM_011529968.2	XP_011528270.1	7, 8	1265
	XM_011529970.2	XP_011528272.1	6, 7	1112
GenBank mRNA	AK309600.1	-	4, 5	1513
	AY663390.1	-	5, 6	804
	BC066877.1	-	6, 7	1029
	BC067432.1	-	7, 8	1182	7002157
	BC075023.2	-	7, 8	1211	30915411
	BC075024.2	-	7, 8	1211	30915622
	BC106757.1	-	6, 7	1050	40024713
	BC106758.1	-	7, 8	1203	40024717
	BC126858.1	-	7, 8	1203	40024719
	BX096000.1	-	1, 2	197
	CR456430.1	-	6, 7	1053
	M20403.1	-	7, 8	1181
	X07618.1	-	5, 6	1072
	X08006.1	-	7, 8	1181

Gene Symbol: CYP2D7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_002570.3		7, 8	1293
GenBank mRNA	AY220845.1	-	8, 9	1355
	X07619.1	-	4, 5	893
	X07620.1	-	3, 4	273
	X16866.1	-	1, 2	285

Gene Symbol: LOC101929829
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_111920.1		7, 8	1270
GenBank mRNA	AB209492.1	-	6, 7	3449
	AK308211.1	-	6, 7	1455
	M24499.1	-	5, 6	809
	X16865.1	-	5, 6	815

More Information

Panther Classification:

Molecular Function -

oxidoreductase, oxygenase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

xenobiotic metabolic process
steroid metabolic process
coumarin metabolic process
alkaloid metabolic process
alkaloid catabolic process
monoterpenoid metabolic process
drug metabolic process
arachidonic acid metabolic process
isoquinoline alkaloid metabolic process
drug catabolic process
heterocycle metabolic process
negative regulation of binding
oxidation-reduction process
oxidative demethylation
negative regulation of cellular organofluorine metabolic process
exogenous drug catabolic process

Function(s)

monooxygenase activity
iron ion binding
drug binding
arachidonic acid epoxygenase activity
steroid hydroxylase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxygen binding
heme binding
aromatase activity