106018

• Gene Symbol: NPC1
• Gene Name: NPC intracellular cholesterol transporter 1
• Gene Aliases: NPC
• Chromosome Location: Chr.18: 23506184 - 23586617 on Build GRCh38
• UniGene ID: Hs.464779
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NPC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000271.4	NP_000262.2	11, 12	2025
	XM_005258277.1	XP_005258334.1	11, 12	1965
	XM_005258278.4	XP_005258335.1	11, 12	1965
	XM_005258279.2	XP_005258336.1	11, 12	1914
	XM_006722479.3	XP_006722542.1	11, 12	1965
	XM_011526015.1	XP_011524317.1	11, 12	2213
	XM_017025784.1	XP_016881273.1	11, 12	1965
	XM_017025785.1	XP_016881274.1	11, 12	1965
	XM_017025786.1	XP_016881275.1	11, 12	1914
	XM_017025787.1	XP_016881276.1	11, 12	1914
GenBank mRNA	AB209048.1	-	11, 12	1786
	AB971140.1	-	11, 12	1751
	AF002020.1	-	11, 12	1874
	AK295715.1	-	9, 10	1665
	BC063302.1	-	11, 12	1848	30340517

More Information

Gene Ontology Categories:

Process(es)

protein glycosylation
endocytosis
autophagy
lysosomal transport
signal transduction
adult walking behavior
cholesterol metabolic process
bile acid metabolic process
negative regulation of macroautophagy
cholesterol transport
membrane raft organization
cholesterol efflux
response to drug
cholesterol homeostasis
response to cadmium ion
viral entry into host cell
negative regulation of cell death
cellular response to steroid hormone stimulus
cellular response to low-density lipoprotein particle stimulus
establishment of protein localization to membrane
positive regulation of cholesterol homeostasis

Function(s)

virus receptor activity
receptor activity
transmembrane signaling receptor activity
protein binding
sterol transporter activity
cholesterol binding