106368

• Gene Symbol: TOP2B
• Gene Name: topoisomerase (DNA) II beta
• Gene Aliases: TOPIIB, top2beta
• Chromosome Location: Chr.3: 25597905 - 25664936 on Build GRCh38
• UniGene ID: Hs.475733
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TOP2B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001068.3	NP_001059.2	26, 27	3576
	XM_005265427.3	XP_005265484.1	26, 27	4155
	XM_011534057.2	XP_011532359.1	26, 27	3565
GenBank mRNA	AB208879.1	-	23, 24	3134
	AK296510.1	-	27, 28	3631
	AK297171.1	-	2, 3	373
	AK316492.1	-	2, 3	326
	BC021863.1	-	1, 2	95
	X53662.1	-	3, 4	390
	X68060.1	-	26, 27	3501
	Z15115.1	-	12, 13	1731

More Information

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

resolution of meiotic recombination intermediates
sister chromatid segregation
neuron migration
DNA topological change
DNA unwinding involved in DNA replication
mitotic recombination
axonogenesis
protein sumoylation
forebrain development
mitotic DNA integrity checkpoint

Function(s)

chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity