106762 Validated

• Gene Symbol: LRP1
• Gene Name: LDL receptor related protein 1
• Gene Aliases: A2MR, APOER, APR, CD91, IGFBP3R, LRP, LRP1A, TGFBR5
• Chromosome Location: Chr.12: 57128401 - 57213377 on Build GRCh38
• UniGene ID: Hs.162757
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: LRP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002332.2	NP_002323.2	11, 12	2268
	XM_017019303.1	XP_016874792.1	11, 12	2366
GenBank mRNA	AB209498.1	-	10, 11	1668
	X13916.1	-	11, 12	2268

More Information

Matching Taqman Gene Expression Assay:

Hs00233856_m1

Panther Classification:

Molecular Function -

apolipoprotein

Gene Ontology Categories:

Process(es)

retinoid metabolic process
receptor-mediated endocytosis
protein kinase C-activating G-protein coupled receptor signaling pathway
aging
cell proliferation
positive regulation of cholesterol efflux
negative regulation of neuron projection development
negative regulation of smooth muscle cell migration
cerebral cortex development
negative regulation of Wnt signaling pathway
positive regulation of lipid transport
regulation of cholesterol transport
regulation of phospholipase A2 activity
regulation of actin cytoskeleton organization
aorta morphogenesis
lipoprotein metabolic process
lipoprotein transport
apoptotic cell clearance
negative regulation of neuron apoptotic process
positive regulation of protein transport
beta-amyloid clearance
negative regulation of platelet-derived growth factor receptor-beta signaling pathway

Function(s)

protease binding
receptor activity
low-density lipoprotein receptor activity
calcium ion binding
protein binding
protein complex binding
apolipoprotein binding
lipoprotein transporter activity
poly(A) RNA binding
lipoprotein particle receptor binding