106765

• Gene Symbol: LRP5
• Gene Name: LDL receptor related protein 5
• Gene Aliases: BMND1, EVR1, EVR4, HBM, LR3, LRP-5, LRP7, OPPG, OPS, OPTA1, VBCH2
• Chromosome Location: Chr.11: 68298866 - 68449275 on Build GRCh38
• UniGene ID: Hs.6347
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: LRP5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001291902.1	NP_001278831.1	23	5130
	NM_002335.3	NP_002326.2	23	5108
	XM_005273994.2	XP_005274051.1	24	5217
	XM_011545029.1	XP_011543331.1	24	5158
	XM_011545030.1	XP_011543332.1	23	5044
	XM_011545031.1	XP_011543333.1	24	5174
	XM_017017735.1	XP_016873224.1	17	3438
	XM_017017736.1	XP_016873225.1	14	2821
GenBank mRNA	AF064548.1	-	23	5050
	AF077820.1	-	23	5090
	BC098397.1	-	23	5055

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

gastrulation with mouth forming second
positive regulation of mesenchymal cell proliferation
osteoblast development
glucose catabolic process
endocytosis
cholesterol metabolic process
regulation of blood pressure
positive regulation of cell proliferation
anterior/posterior pattern specification
Wnt signaling pathway
positive regulation of osteoblast proliferation
somatic stem cell population maintenance
extracellular matrix-cell signaling
cell migration involved in gastrulation
cholesterol homeostasis
embryonic digit morphogenesis
regulation of apoptotic process
Wnt signaling pathway involved in dorsal/ventral axis specification
positive regulation of fat cell differentiation
negative regulation of osteoblast differentiation
positive regulation of mitotic nuclear division
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
bone remodeling
regulation of bone remodeling
bone marrow development
positive regulation of sequence-specific DNA binding transcription factor activity
anatomical structure regression
retina morphogenesis in camera-type eye
canonical Wnt signaling pathway
bone morphogenesis
branching involved in mammary gland duct morphogenesis
adipose tissue development
cell-cell signaling involved in mammary gland development
regulation of canonical Wnt signaling pathway
regulation of insulin secretion involved in cellular response to glucose stimulus
retinal blood vessel morphogenesis
negative regulation of protein serine/threonine kinase activity
apoptotic process involved in patterning of blood vessels
beta-catenin destruction complex disassembly

Function(s)

protein binding
Wnt-protein binding
toxin transporter activity
Wnt-activated receptor activity
coreceptor activity involved in Wnt signaling pathway
coreceptor activity involved in canonical Wnt signaling pathway