106815

• Gene Symbol: IRF4
• Gene Name: interferon regulatory factor 4
• Gene Aliases: LSIRF, MUM1, NF-EM5, SHEP8
• Chromosome Location: Chr.6: 391739 - 411443 on Build GRCh38
• UniGene ID: Hs.401013
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IRF4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001195286.1	NP_001182215.1	6	776
	NM_002460.3	NP_002451.2	6	779
	NR_046000.2		6	776
GenBank mRNA	AK130762.1	-	3	670
	AK310149.1	-	6	766
	BC015752.1	-	6	726	4861223
	D78261.1	-	6	745
	U52682.1	-	6	775
	U63738.1	-	6	758

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106108, XM_006253899.
This siRNA also targets the following transcripts in Mouse: NM_013674, BC137713, U34307, U11692, AK154138, and others.

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
peptidyl-lysine methylation
negative regulation of toll-like receptor signaling pathway
T cell activation
defense response to protozoan
myeloid dendritic cell differentiation
positive regulation of DNA binding
histone H3 acetylation
histone H4 acetylation
positive regulation of interleukin-10 biosynthetic process
positive regulation of interleukin-2 biosynthetic process
positive regulation of interleukin-13 biosynthetic process
positive regulation of interleukin-4 biosynthetic process
regulation of T-helper cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
T-helper 17 cell lineage commitment

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein-lysine N-methyltransferase activity
sequence-specific DNA binding