107665

• Gene Symbol: MECOM
• Gene Name: MDS1 and EVI1 complex locus
• Gene Aliases: AML1-EVI-1, EVI1, MDS1, MDS1-EVI1, PRDM3, RUSAT2
• Chromosome Location: Chr.3: 169083499 - 169663781 on Build GRCh38
• UniGene ID: Hs.744090
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MECOM
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001105077.3	NP_001098547.3	8	1049
	NM_001105078.3	NP_001098548.2	7	1040
	NM_001163999.1	NP_001157471.1	7	987
	NM_001164000.1	NP_001157472.1	7	1916
	NM_001205194.1	NP_001192123.1	7	1344
	NM_004991.3	NP_004982.2	8	1682
	NM_005241.3	NP_005232.2	7	984
	XM_005247213.3	XP_005247270.1	8	1691
	XM_005247214.3	XP_005247271.1	8	1691
	XM_005247215.3	XP_005247272.1	8	1687
	XM_005247219.2	XP_005247276.1	7	1656
	XM_005247220.2	XP_005247277.1	7	997
	XM_005247221.2	XP_005247278.1	7	980
	XM_005247223.2	XP_005247280.1	7	1653
	XM_011512546.2	XP_011510848.1	7	1444
	XM_017005874.1	XP_016861363.1	7	2359
	XM_017005875.1	XP_016861364.1	7	994
	XM_017005876.1	XP_016861365.1	7	1656
GenBank mRNA	AK292865.1	-	7	967
	AK304098.1	-	8	1628
	AK308404.1	-	8	1327
	AK310509.1	-	6	828
	BC130520.1	-	8	1023	40146551
	BC143951.1	-	8	1023	9052469
	BC143952.1	-	7	961	9052470
	BX640908.1	-	7	1916
	BX647613.1	-	7	1648
	GQ352634.1	-	7	1248
	X54989.1	-	7	982

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106423, XM_006232249, XM_008760909, XM_008760910, XM_006232250, and others.
This siRNA also targets the following transcripts in Mouse: AJ001482, JQ665270.

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
apoptotic process
cell differentiation
histone lysine methylation
negative regulation of programmed cell death
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of JNK cascade
regulation of cell cycle
hematopoietic stem cell proliferation

Function(s)

DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
histone-lysine N-methyltransferase activity
metal ion binding