107821

• Gene Symbol: TOB1
• Gene Name: transducer of ERBB2, 1
• Gene Aliases: APRO5, APRO6, PIG49, TOB, TROB, TROB1
• Chromosome Location: Chr.17: 50862223 - 50867978 on Build GRCh38
• UniGene ID: Hs.703321
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TOB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001243877.1	NP_001230806.1	3	1284
	NM_001243885.1	NP_001230814.1	2	1095
	NM_005749.3	NP_005740.1	2	1298
GenBank mRNA	AK313904.1	-	3	1285
	AY524047.1	-	1	865
	BC031406.1	-	1	862	5194914
	BC070493.1	-	2	1286	6470511
	BC098415.1	-	2	1290	6480318
	BT019380.1	-	1	855
	BT019381.1	-	1	855
	CR536487.1	-	1	855
	CR541686.1	-	1	855
	D38305.1	-	1	898

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_133317, AF349723.
This siRNA also targets the following transcripts in Mouse: NM_009427, BC082588, AK142667.

Gene Ontology Categories:

Process(es)

SMAD protein import into nucleus
negative regulation of cell proliferation
positive regulation of signal transduction
negative regulation of translation
negative regulation of BMP signaling pathway
negative regulation of osteoblast differentiation
negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
negative regulation of nucleic acid-templated transcription

Function(s)

transcription corepressor activity
SH3/SH2 adaptor activity
protein binding
receptor tyrosine kinase binding
SMAD binding