108362

• Gene Symbol: STAT5B
• Gene Name: signal transducer and activator of transcription 5B
• Gene Aliases: STAT5
• Chromosome Location: Chr.17: 42199177 - 42276460 on Build GRCh38
• UniGene ID: Hs.595276
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: STAT5B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012448.3	NP_036580.2	14	1870
	XM_017024977.1	XP_016880466.1	13	1689
GenBank mRNA	AB208920.1	-	14	1849
	AK308163.1	-	14	1758
	BC065227.1	-	14	1870	5553426
	U47686.1	-	14	1847
	U48730.2	-	13	1712

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022380, X97541, X91988.
This siRNA also targets the following transcripts in Mouse: NM_011489, NM_001113563, Z48539, AK154664, AK045531, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

allantoin metabolic process
luteinization
response to hypoxia
natural killer cell differentiation
liver development
citrate metabolic process
2-oxoglutarate metabolic process
succinate metabolic process
oxaloacetate metabolic process
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
isoleucine metabolic process
valine metabolic process
creatine metabolic process
fatty acid metabolic process
acute-phase response
JAK-STAT cascade
female pregnancy
lactation
peptidyl-tyrosine phosphorylation
regulation of steroid metabolic process
taurine metabolic process
lipid storage
regulation of epithelial cell differentiation
response to estradiol
response to lipopolysaccharide
positive regulation of natural killer cell proliferation
positive regulation of natural killer cell differentiation
cellular response to hormone stimulus
T cell differentiation in thymus
prolactin signaling pathway
regulation of multicellular organism growth
positive regulation of multicellular organism growth
positive regulation of activated T cell proliferation
progesterone metabolic process
T cell homeostasis
negative regulation of apoptotic process
positive regulation of interleukin-2 biosynthetic process
response to ethanol
positive regulation of B cell differentiation
positive regulation of gamma-delta T cell differentiation
negative regulation of erythrocyte differentiation
positive regulation of erythrocyte differentiation
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
positive regulation of natural killer cell mediated cytotoxicity
creatinine metabolic process
development of secondary female sexual characteristics
development of secondary male sexual characteristics
Peyer's patch development
positive regulation of smooth muscle cell proliferation
positive regulation of inflammatory response
positive regulation of cellular component movement
JAK-STAT cascade involved in growth hormone signaling pathway
response to interleukin-2
response to interleukin-4
response to interleukin-15
cellular response to growth factor stimulus
cellular response to epidermal growth factor stimulus
mast cell migration

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein tyrosine kinase activity
signal transducer activity
protein binding
protein phosphatase binding
glucocorticoid receptor binding
protein dimerization activity