109468

• Gene Symbol: NSD1
• Gene Name: nuclear receptor binding SET domain protein 1
• Gene Aliases: ARA267, KMT3B, SOTOS, SOTOS1, STO
• Chromosome Location: Chr.5: 177133079 - 177300213 on Build GRCh38
• UniGene ID: Hs.106861
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NSD1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022455.4	NP_071900.2	4, 5	1368
	NM_172349.2	NP_758859.1	5, 6	583
GenBank mRNA	AF380302.1	-	5, 6	524
	AF395588.1	-	4, 5	1275
	AK056667.1	-	3, 4	347
	AY049721.1	-	3, 4	1248
	BC139789.1	-	4, 5	453
	BC144629.1	-	5, 6	813
	BC150628.1	-	4, 5	458	9056998

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001107337, XM_008771494, XM_006253627, XM_006253620, XM_006253621, and others.
This siRNA also targets the following transcripts in Mouse: NM_008739, BY389912, AK145783.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of histone H3-K36 methylation
transcription, DNA-templated
histone H3-K36 methylation
histone methylation
regulation of peptidyl-serine phosphorylation
histone H4-K20 methylation
positive regulation of transcription, DNA-templated
regulation of RNA polymerase II regulatory region sequence-specific DNA binding

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
chromatin binding
transcription cofactor activity
transcription corepressor activity
zinc ion binding
histone-lysine N-methyltransferase activity
estrogen receptor binding
histone methyltransferase activity (H4-K20 specific)
retinoic acid receptor binding
retinoid X receptor binding
thyroid hormone receptor binding
histone methyltransferase activity (H3-K36 specific)
androgen receptor binding