110717

• Gene Symbol: DHFR
• Gene Name: dihydrofolate reductase
• Gene Aliases: DHFRP1, DYR
• Chromosome Location: Chr.5: 80626226 - 80654981 on Build GRCh38
• UniGene ID: Hs.592364
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DHFR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000791.3	NP_000782.1	6	1639
	NM_001290354.1	NP_001277283.1	5	1589
	NM_001290357.1	NP_001277286.1	5	1523
	NR_110936.1		4	1462
GenBank mRNA	AK293146.1	-	5	1167
	AK297302.1	-	5	1094
	BC000192.1	-	6	1202	3352539

More Information

Panther Classification:

Molecular Function -

reductase

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
glycine biosynthetic process
tetrahydrobiopterin biosynthetic process
one-carbon metabolic process
nucleotide biosynthetic process
axon regeneration
response to methotrexate
dihydrofolate metabolic process
tetrahydrofolate metabolic process
tetrahydrofolate biosynthetic process
folic acid metabolic process
positive regulation of nitric-oxide synthase activity
oxidation-reduction process
regulation of removal of superoxide radicals

Function(s)

mRNA binding
dihydrofolate reductase activity
folic acid binding
drug binding
folate reductase activity
methotrexate binding
NADPH binding