110728

• Gene Symbol: FGFR3
• Gene Name: fibroblast growth factor receptor 3
• Gene Aliases: ACH, CD333, CEK2, HSFGFR3EX, JTK4
• Chromosome Location: Chr.4: 1793299 - 1808872 on Build GRCh38
• UniGene ID: Hs.1420
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FGFR3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000142.4	NP_000133.1	18	4231
	NM_001163213.1	NP_001156685.1	18	4237
	NM_022965.3	NP_075254.1	16	3895
	XM_006713868.1	XP_006713931.1	18	4259
	XM_006713869.1	XP_006713932.1	18	4256
	XM_006713870.1	XP_006713933.1	18	4256
	XM_006713871.1	XP_006713934.1	18	4253
	XM_006713872.1	XP_006713935.1	18	4247
	XM_006713873.1	XP_006713936.1	18	4247
	XM_011513420.1	XP_011511722.1	18	4253
	XM_011513422.1	XP_011511724.1	18	4250
GenBank mRNA	AB209441.1	-	17	4166
	M64347.1	-	16	3744

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
skeletal system development
endochondral ossification
chondrocyte differentiation
endochondral bone growth
JAK-STAT cascade
cell-cell signaling
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of phospholipase activity
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
bone mineralization
chondrocyte proliferation
phosphatidylinositol-3-phosphate biosynthetic process
positive regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of MAPK cascade
positive regulation of GTPase activity
positive regulation of phosphatidylinositol 3-kinase activity
protein autophosphorylation
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
negative regulation of developmental growth
bone morphogenesis
positive regulation of ERK1 and ERK2 cascade
bone maturation
fibroblast growth factor receptor apoptotic signaling pathway

Function(s)

protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
fibroblast growth factor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity