110841 Validated

• Gene Symbol: TOP2B
• Gene Name: topoisomerase (DNA) II beta
• Gene Aliases: TOPIIB, top2beta
• Chromosome Location: Chr.3: 25597905 - 25664936 on Build GRCh38
• UniGene ID: Hs.475733
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TOP2B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001068.3	NP_001059.2	2, 3	304
	XM_005265427.3	XP_005265484.1	2, 3	883
	XM_011534057.2	XP_011532359.1	2, 3	293
GenBank mRNA	AK296510.1	-	3, 4	359
	AK307450.1	-	4, 5	304
	BM150930.1	-	2, 3	432
	X68060.1	-	2, 3	229
	Z15111.1	-	2, 3	229

More Information

Matching Taqman Gene Expression Assay:

Hs00172259_m1

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

resolution of meiotic recombination intermediates
sister chromatid segregation
neuron migration
DNA topological change
DNA unwinding involved in DNA replication
mitotic recombination
axonogenesis
protein sumoylation
forebrain development
mitotic DNA integrity checkpoint

Function(s)

chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity