110846

• Gene Symbol: BRAF
• Gene Name: B-Raf proto-oncogene, serine/threonine kinase
• Gene Aliases: B-RAF1, B-raf, BRAF1, NS7, RAFB1
• Chromosome Location: Chr.7: 140719331 - 140924764 on Build GRCh38
• UniGene ID: Hs.550061
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BRAF
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004333.4	NP_004324.2	2	255
	XM_005250045.2	XP_005250102.1	2	202
	XM_017012558.1	XP_016868047.1	2	202
	XM_017012559.1	XP_016868048.1	2	202
GenBank mRNA	AI203435.1	-	2	227
	AK314346.1	-	2	202
	BC101757.1	-	2	216	8069263
	BC112079.1	-	2	216	8327547
	DB454480.1	-	2	420
	DN996440.1	-	2	453
	M95712.2	-	2	255

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_139294, BF466677, AK140431.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
myeloid progenitor cell differentiation
protein phosphorylation
visual learning
organ morphogenesis
positive regulation of gene expression
negative regulation of fibroblast migration
glucose transport
thyroid gland development
positive regulation of peptidyl-serine phosphorylation
somatic stem cell population maintenance
cellular response to drug
regulation of cell proliferation
negative regulation of apoptotic process
CD4-positive, alpha-beta T cell differentiation
positive T cell selection
response to peptide hormone
negative regulation of neuron apoptotic process
thymus development
positive regulation of axon regeneration
positive regulation of axonogenesis
protein heterooligomerization
positive regulation of stress fiber assembly
response to cAMP
long-term synaptic potentiation
head morphogenesis
face development
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
establishment of protein localization to membrane
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of synaptic vesicle exocytosis
negative regulation of endothelial cell apoptotic process

Function(s)

protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
small GTPase binding
mitogen-activated protein kinase kinase binding
identical protein binding
protein heterodimerization activity