110913

• Gene Symbol: DDR2
• Gene Name: discoidin domain receptor tyrosine kinase 2
• Gene Aliases: MIG20a, NTRKR3, TKT, TYRO10
• Chromosome Location: Chr.1: 162631213 - 162783524 on Build GRCh38
• UniGene ID: Hs.275757
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DDR2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001014796.1	NP_001014796.1	18	2861
	NM_006182.2	NP_006173.2	17	2781
	XM_006711344.3	XP_006711407.1	17	2822
	XM_011509586.2	XP_011507888.1	17	2754
	XM_011509587.2	XP_011507889.1	18	2815
GenBank mRNA	AA148473.1	-	1	41
	AK095975.1	-	18	2834
	AK225063.1	-	17	2700
	AK225196.1	-	11	1541
	AK314388.1	-	17	2730
	BC052998.2	-	18	2832	6162716
	BX640899.1	-	18	2818
	X74764.1	-	17	2749

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031764, XM_006250227, XM_008769762, XM_006250226, XM_008769763, and others.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

ossification
endochondral bone growth
cell adhesion
signal transduction
regulation of extracellular matrix disassembly
positive regulation of fibroblast migration
peptidyl-tyrosine phosphorylation
extracellular matrix organization
collagen fibril organization
regulation of bone mineralization
biomineral tissue development
chondrocyte proliferation
collagen-activated tyrosine kinase receptor signaling pathway
positive regulation of osteoblast differentiation
positive regulation of protein kinase activity
protein autophosphorylation
positive regulation of fibroblast proliferation
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of extracellular matrix disassembly

Function(s)

transmembrane receptor protein tyrosine kinase activity
protein binding
collagen binding
ATP binding
protein tyrosine kinase collagen receptor activity