111118

• Gene Symbol: ITGAV
• Gene Name: integrin subunit alpha V
• Gene Aliases: CD51, MSK8, VNRA, VTNR
• Chromosome Location: Chr.2: 186590063 - 186680902 on Build GRCh38
• UniGene ID: Hs.436873
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ITGAV
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001144999.2	NP_001138471.1	5, 6	569
	NM_002210.4	NP_002201.1	5, 6	853
GenBank mRNA	AK302550.1	-	5, 6	853
	AK302990.1	-	5, 6	569
	AK309711.1	-	5, 6	853
	BC126231.1	-	5, 6	706	8991947
	BC136442.1	-	5, 6	706	9020431
	EF560727.1	-	5, 6	621
	M14648.1	-	5, 6	618

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008762000.
This siRNA also targets the following transcripts in Mouse: NM_008402, BC133682, U14135, AK149984.

Panther Classification:

Molecular Function -

integrin

Gene Ontology Categories:

Process(es)

angiogenesis
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
positive regulation of cell proliferation
negative regulation of macrophage derived foam cell differentiation
negative regulation of lipid storage
cell growth
cell migration
extracellular matrix organization
positive regulation of cell migration
cell-substrate adhesion
negative regulation of lipid transport
positive regulation of osteoblast proliferation
heterotypic cell-cell adhesion
substrate adhesion-dependent cell spreading
endodermal cell differentiation
apolipoprotein A-I-mediated signaling pathway
apoptotic cell clearance
negative regulation of low-density lipoprotein particle receptor biosynthetic process
positive regulation of cell adhesion
viral entry into host cell
vascular endothelial growth factor receptor signaling pathway
negative regulation of lipoprotein metabolic process
regulation of phagocytosis
leukocyte migration
negative chemotaxis
entry of symbiont into host cell by promotion of host phagocytosis
ERK1 and ERK2 cascade
calcium ion transmembrane transport
extrinsic apoptotic signaling pathway in absence of ligand
regulation of apoptotic cell clearance
negative regulation of entry of bacterium into host cell
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

virus receptor activity
opsonin binding
fibronectin binding
protease binding
protein kinase C binding
voltage-gated calcium channel activity
protein binding
coreceptor activity
fibroblast growth factor binding
C-X3-C chemokine binding
insulin-like growth factor I binding
neuregulin binding
metal ion binding
transforming growth factor beta binding
extracellular matrix binding
extracellular matrix protein binding