11116

• Gene Symbol: JUP
• Gene Name: junction plakoglobin
• Gene Aliases: ARVD12, CTNNG, DP3, DPIII, PDGB, PKGB
• Chromosome Location: Chr.17: 41754607 - 41786853 on Build GRCh38
• UniGene ID: Hs.514174
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: JUP
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002230.2	NP_002221.1	2	261
	NM_021991.2	NP_068831.1	2	261
	XM_006721873.2	XP_006721936.1	3	511
	XM_006721874.2	XP_006721937.1	2	424
	XM_006721875.1	XP_006721938.1	2	343
	XM_006721878.1	XP_006721941.1	2	324
	XM_011524753.2	XP_011523055.1	3	547
	XM_011524755.1	XP_011523057.1	2	256
	XM_011524756.1	XP_011523058.1	2	154
	XM_011524757.2	XP_011523059.1	2	421
	XM_011524758.1	XP_011523060.1	2	150
	XM_017024588.1	XP_016880077.1	2	243
	XM_017024589.1	XP_016880078.1	2	244
	XM_017024590.1	XP_016880079.1	2	150
GenBank mRNA	AK226051.1	-	2	238
	AY243535.1	-	1	134
	BC000441.2	-	2	247
	BC011865.2	-	2	405	4542042
	KU178155.1	-	1	128
	M23410.1	-	2	247
	Z68228.1	-	2	247

More Information

Gene Ontology Categories:

Process(es)

desmosome assembly
cytoskeletal anchoring at plasma membrane
signal transduction
single organismal cell-cell adhesion
cell migration
adherens junction organization
adherens junction assembly
regulation of cell proliferation
positive regulation of protein import into nucleus
skin development
detection of mechanical stimulus
positive regulation of sequence-specific DNA binding transcription factor activity
protein heterooligomerization
endothelial cell-cell adhesion
cellular response to indole-3-methanol
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
establishment of protein localization to plasma membrane
positive regulation of canonical Wnt signaling pathway
regulation of ventricular cardiac muscle cell action potential

Function(s)

transcription coactivator activity
signal transducer activity
structural molecule activity
structural constituent of cell wall
protein binding
protein kinase binding
protein phosphatase binding
protein homodimerization activity
alpha-catenin binding
cadherin binding
cell adhesion molecule binding
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
cadherin binding involved in cell-cell adhesion