111293 Validated

• Gene Symbol: TOP1
• Gene Name: topoisomerase (DNA) I
• Gene Aliases: TOPI
• Chromosome Location: Chr.20: 41028822 - 41124487 on Build GRCh38
• UniGene ID: Hs.472737
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TOP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003286.2	NP_003277.1	4, 5	519
GenBank mRNA	AK225095.1	-	4, 5	518
	AK292943.1	-	4, 5	518
	AK310508.1	-	3, 4	401
	BC004475.2	-	4, 5	501
	BC067349.1	-	4, 5	498
	BC136297.1	-	4, 5	370	9020284
	J03250.1	-	4, 5	484
	U07804.1	-	4, 5	263
	U07806.1	-	4, 5	263

More Information

Matching Taqman Gene Expression Assay:

Hs00243257_m1

Panther Classification:

Molecular Function -

DNA topoisomerase

Gene Ontology Categories:

Process(es)

DNA replication
DNA topological change
chromatin remodeling
chromosome segregation
circadian rhythm
programmed cell death
viral process
phosphorylation
protein sumoylation
circadian regulation of gene expression
embryonic cleavage
response to drug

Function(s)

core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase type I activity
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein binding
poly(A) RNA binding