111294 Validated

• Gene Symbol: TOP1
• Gene Name: topoisomerase (DNA) I
• Gene Aliases: TOPI
• Chromosome Location: Chr.20: 41028822 - 41124487 on Build GRCh38
• UniGene ID: Hs.472737
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TOP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003286.2	NP_003277.1	9	950
GenBank mRNA	AK292943.1	-	9	949
	AK310508.1	-	8	832
	BC136297.1	-	9	801	9020284
	J03250.1	-	9	915
	U07804.1	-	9	694
	U07806.1	-	9	694

More Information

Matching Taqman Gene Expression Assay:

Hs00243257_m1

Panther Classification:

Molecular Function -

DNA topoisomerase

Gene Ontology Categories:

Process(es)

DNA replication
DNA topological change
chromatin remodeling
chromosome segregation
circadian rhythm
programmed cell death
viral process
phosphorylation
protein sumoylation
circadian regulation of gene expression
embryonic cleavage
response to drug

Function(s)

core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase type I activity
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein binding
poly(A) RNA binding