111382

• Gene Symbol: TNFRSF10B
• Gene Name: TNF receptor superfamily member 10b
• Gene Aliases: CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
• Chromosome Location: Chr.8: 23020133 - 23069187 on Build GRCh38
• UniGene ID: Hs.521456
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TNFRSF10B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003842.4	NP_003833.4	9	1818
	NM_147187.2	NP_671716.2	10	1731
	NR_027140.1		9	1625
	XM_017013944.1	XP_016869433.1	9	1606
GenBank mRNA	AF012535.1	-	10	1577
	AF016266.1	-	9	1642
	AF016268.1	-	10	1547
	AF016849.1	-	9	1669
	AF153687.1	-	10	1556
	AF192548.1	-	10	1538
	AK291216.1	-	9	1645
	AK296128.1	-	5	832
	AY358277.1	-	10	1577
	BC001281.1	-	9	1672	3458466
	BX537617.1	-	4	923
	BX538104.1	-	9	1647
	BX538179.1	-	4	923

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
immune response
cell surface receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
response to endoplasmic reticulum stress
regulation of cell proliferation
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to mechanical stimulus
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

receptor activity
tumor necrosis factor-activated receptor activity
protein binding
TRAIL binding