111985

• Gene Symbol: TLR8
• Gene Name: toll like receptor 8
• Gene Aliases: CD288
• Chromosome Location: Chr.X: 12906620 - 12923169 on Build GRCh38
• UniGene ID: Hs.660543
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TLR8
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_016610.3	NP_057694.2	3	468
	NM_138636.5	NP_619542.1	2	331
	XM_011545529.1	XP_011543831.1	3	619
	XM_011545530.2	XP_011543832.1	3	447
GenBank mRNA	AB445666.1	-	1	244
	AF245703.1	-	2	292
	AF246971.1	-	3	449
	AK314240.1	-	2	332
	AY358296.1	-	2	300
	BC101074.1	-	2	298	40008787
	BC101075.2	-	2	298	40008788
	BC101076.2	-	2	298	40008792
	BC101077.1	-	2	298	40008793

More Information

Gene Ontology Categories:

Process(es)

microglial cell activation
regulation of protein phosphorylation
toll-like receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
inflammatory response
I-kappaB kinase/NF-kappaB signaling
response to virus
immunoglobulin mediated immune response
toll-like receptor 8 signaling pathway
toll-like receptor 9 signaling pathway
positive regulation of interferon-gamma biosynthetic process
innate immune response
positive regulation of innate immune response
positive regulation of interferon-alpha biosynthetic process
positive regulation of interferon-beta biosynthetic process
positive regulation of interleukin-8 biosynthetic process
regulation of cytokine secretion
defense response to virus
cellular response to mechanical stimulus

Function(s)

DNA binding
RNA binding
double-stranded RNA binding
single-stranded RNA binding
receptor activity
drug binding