111998

• Gene Symbol: TLR9
• Gene Name: toll like receptor 9
• Gene Aliases: CD289
• Chromosome Location: Chr.3: 52221080 - 52226163 on Build GRCh38
• UniGene ID: Hs.87968
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TLR9
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_017442.3	NP_059138.1	2	1167
GenBank mRNA	AB045180.1	-	2	639
	AB445673.1	-	1	533
	AF245704.1	-	2	677
	AF246972.1	-	1	602
	AF259262.1	-	2	1167
	AF259263.1	-	1	409
	AY359085.1	-	1	543
	BC032713.1	-	2	629	5495717

More Information

Gene Ontology Categories:

Process(es)

toll-like receptor signaling pathway
response to molecule of bacterial origin
MyD88-dependent toll-like receptor signaling pathway
inflammatory response
I-kappaB phosphorylation
axonogenesis
positive regulation of gene expression
maintenance of gastrointestinal epithelium
negative regulation of NF-kappaB transcription factor activity
tumor necrosis factor production
negative regulation of interleukin-6 production
negative regulation of interleukin-8 production
positive regulation of chemokine production
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interferon-beta production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
positive regulation of interleukin-18 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
negative regulation of toll-like receptor signaling pathway
positive regulation of toll-like receptor signaling pathway
toll-like receptor 9 signaling pathway
phosphatidylinositol-3-phosphate biosynthetic process
positive regulation of NF-kappaB import into nucleus
defense response to bacterium
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JUN kinase activity
positive regulation of interferon-gamma biosynthetic process
innate immune response
positive regulation of interferon-alpha biosynthetic process
positive regulation of interferon-beta biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
regulation of cytokine secretion
positive regulation of inflammatory response
defense response to Gram-negative bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of nitric-oxide synthase biosynthetic process
negative regulation of calcium-transporting ATPase activity

Function(s)

transmembrane signaling receptor activity
interleukin-1 receptor binding
1-phosphatidylinositol-3-kinase activity
siRNA binding