112291

• Gene Symbol: ITGB1
• Gene Name: integrin subunit beta 1
• Gene Aliases: CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB
• Chromosome Location: Chr.10: 32900318 - 32958365 on Build GRCh38
• UniGene ID: Hs.643813
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ITGB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002211.3	NP_002202.2	3	350
	NM_033668.2	NP_391988.1	2	129
	NM_133376.2	NP_596867.1	3	265
GenBank mRNA	AK291697.1	-	3	202
	AL710802.1	-	2	141
	BC020057.1	-	3	194	3924411
	BX537407.1	-	3	204
	DB292597.1	-	3	205

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017022, XM_006255824, BC131845, U12309.
This siRNA also targets the following transcripts in Mouse: NM_010578, BC050906, X15202, AK167682, AK088729, and others.

Panther Classification:

Molecular Function -

integrin

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
in utero embryonic development
cell fate specification
tissue homeostasis
cell migration involved in sprouting angiogenesis
cellular calcium ion homeostasis
cellular defense response
homophilic cell adhesion via plasma membrane adhesion molecules
leukocyte cell-cell adhesion
cell-matrix adhesion
calcium-independent cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of cell proliferation
negative regulation of cell proliferation
germ cell migration
visual learning
regulation of collagen catabolic process
positive regulation of cell-substrate adhesion
positive regulation of neuron projection development
response to activity
cell migration
formation of radial glial scaffolds
B cell differentiation
extracellular matrix organization
positive regulation of cell migration
negative regulation of cell projection organization
cell-substrate adhesion
receptor internalization
protein transport within lipid bilayer
cell-cell adhesion mediated by integrin
heterotypic cell-cell adhesion
response to gonadotropin
negative regulation of Rho protein signal transduction
response to drug
positive regulation of apoptotic process
stress fiber assembly
positive regulation of MAPK cascade
positive regulation of GTPase activity
sarcomere organization
negative regulation of neuron differentiation
positive regulation of endocytosis
viral entry into host cell
mesodermal cell differentiation
axon extension
dendrite morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
regulation of immune response
leukocyte migration
leukocyte tethering or rolling
regulation of cell cycle
cardiac muscle cell differentiation
maternal process involved in female pregnancy
bicellular tight junction assembly
cellular response to mechanical stimulus
cellular response to vitamin D
cellular response to low-density lipoprotein particle stimulus
cellular response to ionizing radiation
positive regulation of establishment of protein localization to plasma membrane
negative regulation of anoikis

Function(s)

virus receptor activity
glycoprotein binding
fibronectin binding
protease binding
actin binding
integrin binding
protein binding
coreceptor activity
protein kinase binding
protein domain specific binding
C-X3-C chemokine binding
protein complex binding
peptide binding
laminin binding
metal ion binding
protein heterodimerization activity
cell adhesion molecule binding
alpha-actinin binding
collagen binding involved in cell-matrix adhesion
cadherin binding involved in cell-cell adhesion